In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformation. G. Mas, F. Santoro, E. Blanco, G.P. Gamarra-Figueroa, F. Le Dily, G. Frige, E. Vidal, F. Mugianesi, C. Ballare, A. Gutierrez, A. Sparavier, M.A. Marti-Renom, S. Minucci and L. Di Croce. Genes and Development 36:451-467 (2022).

Differential contribution to gene expression prediction of histone modifications at enhancers or promoters. M. Gonzalez-Ramirez, C. Ballare, F. Mugianesi, M. Beringer, A. Santanach, E. Blanco and L. Di Croce. PLoS Computational Biology 17:e1009368 (2021).

SpikChIP: a novel computational methodology to compare multiple ChIP-seq using spike-in chromatin. E. Blanco, L. Di Croce and S. Aranda. NAR Genomics and Bioinformatics 3:lqab064 (2021).

Polycomb factor Phf19 controls cell growth and differentiation towards erythroid pathway in chronic myeloid leukemia cells. M. García-Montolio, C. Ballare, E. Blanco, A. Gutierrez, S. Aranda, A. Gomez, C.H. Kok, D. Yeung, T.P. Hughes, P. Vizan and L. Di Croce. Cell and Developmental Biology 9:655201 (2021).

Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease. R. Alcala-Vida*, M. Garcia-Forn*, C. Castany-Pladevall, J. Creus-Muncunill, Y. Ito, E. Blanco, A. Golbano, K. Crespí-Vázquez, A. Parry, G. Slater, S. Samarajiwa, S. Peiró, L. Di Croce, M. Narita and E. Pérez-Navarro. EMBO Molecular Medicine 13:e12105 (2021).

RING1B recruits EWSR1-1 FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis. S. Sanchez-Molina, E. Figuerola-Bou, E. Blanco, M. Sanchez-Jimenez, P. Taboas, S. Gomez, C. Ballare, D.J. Garcia-Dominguez, E. Prada, L. Hontecillas-Prieto, A. Montero-Carcaboso, O. Tirado, I. Hernandez-Muñoz, E. de Alava, C. Lavarino, L. Di Croce and J. Mora. Science Advances 6: eaba3058 (2020).

The Polycomb-Associated Factor Phf19 Controls Hematopoietic Stem Cell State and Differentiation. P. Vizán*, A. Gutiérrez*, I. Espejo, M. García-Montolio, M. Lange, A. Carretero, A. Lafzi, L. de Andrés-Aguayo, E. Blanco, R. Thambyrajah, T. Graf, H. Heyn, A. Bigas, L. Di Croce. Science Advances 6:eabb2745 (2020).

Trans-generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy. J. Martone, M. Lisi, F. Castagnetti, A. Rosa, V. Di Carlo, E. Blanco, A. Setti,D. Mariani, A. Colantoni, T. Santini, L. Di Croce and I. Bozzoni. EMBO Molecular Medicine e12063 (2020).

PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells. P. Jain, C. Ballare, E, Blanco, P. Vizan and L. Di Croce. Elife 9:e51373 (2020).

The Bivalent Genome: Characterization, Structure, and Regulation. E. Blanco, M. González-Ramírez, A. Alcaine-Colet, S. Aranda and L. Di Croce. Trends in Genetics 36:118-131 (2020).

GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm. J. Castaño, S. Aranda, C. Bueno, F.J. Calero-Nieto, E. Mejia-Ramirez, J.L. Mosquera, E. Blanco, X. Wang, C. Prieto, L. Zabaleta, E. Mereu, M. Rovira, S. Jimenez-Delgado, D.R. Matson, H. Heyn, E.H. Bresnick, B. Gottgens, L. Di Croce, P. Menendez, A. Raya and A. Giorgetti. Stem Cell Reports 13:515-529 (2019).

Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation. S. Aranda, A. Alcaine-Colet, E. Blanco, E. Borràs, C. Caillot, E. Sabidó and L. Di Croce. Science Advances 5:3 (2019)

Promoter bivalency favors an open chromatin architecture in embryonic stem cells. G. Mas, E. Blanco, C. Ballare, M. Sanso, Y. Spill, D. Hu, Y. Aoi, F. Le Dily, A. Shilatifard, M. A. Marti-Renom and L. Di Croce. Nature Genetics 50:1452 (2018)

Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains. L. Pascual-Reguant, E. Blanco, S. Galan, F. Le Dily, Y. Cuartero, G. Serra-Bardenys, V. Di Carlo, A. Iturbide, J.P. Cebrià-Costa, L. Nonell, A. Garcia de Herreros, L. Di Croce, M. Marti-Renom and S. Peiro. Nature Communications 9:3420 (2018)

The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity. A. Santanach, E. Blanco, H. Jiang, K.R. Molloy, M. Sansó, J. LaCava, L. Morey and Luciano Di Croce. Nature Communications 8:1235 (2017)

EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells. M. Beringer, P. Pisano, V. Di Carlo, E. Blanco, Paul Chammas, P. Vizan, A. Gutierrez, S. Aranda, B. Payer, M. Wierer and L. Di Croce. Molecular Cell 64:645-658 (2016)

Polycomb Regulates Mesoderm Cell Fate-Specification in Embryonic Stem Cells through Activation and Repression Mechanisms. L. Morey, A. Santanach, E. Blanco, L. Aloia, E. Nora, B. Bruneau and L. Di Croce. Cell Stem Cell 17:300-315 (2015)